PhD in Bioinformatics
La Trobe University · Melbourne, Australia
Sriram Gummadi
Bioinformatics Researcher · Computational Biologist · Cancer Genomics & Data Science
Master of Data Analytics
Deakin University · Melbourne, Australia
Gummadi S, Chitti SV, Kang T, Petrovska M, Mathivanan S, Fonseka P.
EV Barcode: A Machine Learning Driven Web Resource for Predicting the Cellular Origin of Extracellular Vesicles from Omics Cargo
Journal of Extracellular Vesicles. Accepted.
Gummadi S, Chitti SV, Mathivanan S, Shahi S, Fonseka P.
Bioinformatics tools and databases for extracellular vesicles and particles research
In: Extracellular Vesicles. Springer US; pp. 361–377.
Gummadi S, Chitti SV, Kang T, Shahi S, Mathivanan S, Fonseka P.
ExoCarta 2024: A Web-based Repository of Small Extracellular Vesicles Cargo
Journal of Molecular Biology. 437(15):169218.
Chitti SV*, Gummadi S*, Kang T, Shahi S, Fonseka P, Mathivanan S.
Vesiclepedia 2024: an extracellular vesicles and extracellular particles repository
Nucleic Acids Research. 52(D1):D1694–D1698. *Co-first authors.
Gummadi S, Kang T, Fonseka P, Chitti SV, Ang CS, Mathivanan S.
Pep2Graph: A standalone tool to analyse proteolytic cleavages by proteases from gel-based mass spectrometry data
Proteomics. 22(22):e2200147.
Phan TK, Gummadi S, AK, Poon IKH.
Efferocytosis of apoptotic bodies drives SARS-CoV-2 infection and macrophage inflammation
Nature Communications. 17(1):7535.
Petrovska M, Gummadi S, et al.
TMEM16F is an important regulator of cancer cell-derived extracellular vesicle secretion and function
Journal of Extracellular Vesicles. Accepted.
Chitti SV, Marzan AL, Gummadi S, Fonseka P.
Extracellular vesicles enabling moonlighting proteins
In: Cryptic Enzymes and Moonlighting Proteins. Elsevier.
Marzan AL, Chitti SV, Gummadi S, Kang T, Ang CS, Mathivanan S.
Proteomics analysis of C2C12 myotubes treated with atrophy-inducing cancer cell-derived factors
Proteomics. 24(11):e2300020.
Sanwlani R, Kang T, Gummadi S, Nedeva C, Ang CS, Mathivanan S.
Bovine milk-derived extracellular vesicles enhance doxorubicin sensitivity in triple-negative breast cancer cells by targeting metabolism and STAT signalling
Proteomics. 23(18):e2200482.
Chitti SV, Kang T, Fonseka P, Pathan M, Gummadi S, Mathivanan S.
Proteomic analysis of small extracellular vesicles and soluble secretory proteins from cachexia-inducing and non-inducing cancer cells
Proteomics. 23(15):e2100314.
- Rebuttal: The protective effect of exercise on breast cancer progression is mediated by extracellular vesicles.
- In review: Pulsed priming with the FAK inhibitor narmafotinib enhances chemotherapy response in pancreatic cancer.
- In review: Apoptotic bodies from patients with Sjogren's disease drive atypical memory B cell and macrophage activation.
- In preparation: An omics based approach to elucidate EV biogenesis and secretion genes in cancer progression.
- In preparation: Physical coherence and network analysis reveal ubiquitin ligase NEDD4 as a regulator of extracellular vesicle biogenesis.
- In preparation: Tumour extracellular vesicles CNTN1 promote cancer associated cachexia through Notch signalling.
- In preparation: Caspases 3 and 7 regulate basal extracellular vesicle biogenesis through degradation of proteasomal subunits.
- In preparation: Proteomics analysis of 3T3 L1 adipocytes treated with atrophy inducing cancer cell derived factors.
- In preparation: Dietary and probiotic extracellular vesicles from milk and yogurt regulate cancer progression upon oral administration.
- Prof. Sharad Kumar, University of South Australia
- Prof. Paul Timpson, Garvan Institute
- Prof. Mark Febbraio, Monash University
- A/Prof. Naiyang Fu, University of Melbourne
- Dr Rahul Sanwlani, University of Surrey
- Dr Thanh Kha Phan, La Trobe University
Oral presentation and Early Career Researcher Award finalist, ANZSEV, Wellington.
Oral presentation, ISEV, Vienna.
Oral presentation, LIMS EMCR Symposium, Melbourne.
Two poster presentations, ISEV, Melbourne.
Best Oral Presentation, 22nd INCOB, Brisbane.
Oral presentation, SABE First Year Fest, Melbourne.
- Early Career Researcher Award finalist, ANZSEV 2025.
- LIMS Miller HDR Travel Award, La Trobe University, 2025.
- ECR Travel Award, ANZSEV 2025.
- SABE HDR Travel Award, La Trobe University, 2024.
- Best Oral Presentation, INCOB 2023.
- Full Fee Research Scholarship and Postgraduate Research Scholarship, La Trobe University, 2023.
- Bioinformatics demonstrator, La Trobe University, 2023 to 2026.
- Mentored a Master's by Research student to completion with H1.
- Research Assistant, University of Queensland.
- LIMS EMCR Organising Committee and Workshops Subcommittee, 2023 to 2024.
- Executive member, La Trobe University BioChem Society, 2023 to present.
- International Society for Extracellular Vesicles (ISEV)
- Australia and New Zealand Society of Extracellular Vesicles (ANZSEV)
- Research Centre for Extracellular Vesicles, La Trobe University
- Student Network on Extracellular Vesicles (SNEV)
- American Association of Extracellular Vesicles (AAEV)
- Deconvoluting bulk RNA seq, Single R, 2025
- PyDESeq2 differential expression analysis, 2025
- Machine Learning in Bioinformatics, 2025
- Single Cell Transcriptomics, 2024
- Spatial Transcriptomics, 2024
- Protein Modelling, Targeted Drug Design and Mutation Insights, 2024
- Quantum Machine Learning, 2023
- Advanced R for Bioinformatics, 2023
- Prof. Suresh Mathivanan, La Trobe University
- Dr Pamali Fonseka, La Trobe University
- Professional references available upon request.