RESEARCH PORTFOLIO · 05 PROJECTS

Projects

Complete, figure-led computational studies across transcriptomics, cancer genomics, metagenomics and pharmacogenomics.

Preview of Single-Cell RNA Sequencing of the Human Lung Reveals Disease-Associated Cellular Remodeling and Transcriptional Divergence in IPF and COPD

PROJECT 01 · Single-cell transcriptomics

Single-Cell RNA Sequencing of the Human Lung Reveals Disease-Associated Cellular Remodeling and Transcriptional Divergence in IPF and COPD

TECHNICAL FOCUSR · scRNA-seq · cell-type annotation · pseudobulk differential expression · pathway enrichment · statistical modelling

Preview of Spatial Transcriptomics of Human Breast Cancer Reveals Heterogeneous Immune, Stromal and Hypoxia-Associated Molecular Architecture

Open project ↗

PROJECT 02 · Spatial transcriptomics

Spatial Transcriptomics of Human Breast Cancer Reveals Heterogeneous Immune, Stromal and Hypoxia-Associated Molecular Architecture

TECHNICAL FOCUSPython · Scanpy · spatial gene expression · clustering · tissue architecture · tumour microenvironment analysis · spatial statistics

Preview of A Systematic Cancer-Specific and Pan-Cancer Transcriptomic Analysis: Deciphering Prognostic Gene Associations, Survival Heterogeneity, and Biological Pathways

Open project ↗

PROJECT 03 · Cancer transcriptomics

A Systematic Cancer-Specific and Pan-Cancer Transcriptomic Analysis: Deciphering Prognostic Gene Associations, Survival Heterogeneity, and Biological Pathways

TECHNICAL FOCUSR · cancer genomics · Cox proportional hazards regression · Kaplan–Meier analysis · survival modelling · multiple-testing correction

Preview of A Multi-Cohort Shotgun Metagenomic Investigation of Colorectal Cancer: Microbial Diversity, Biomarker Discovery, Functional Metagenomics and Independent Validation

Open project ↗

PROJECT 04 · Microbiome metagenomics

A Multi-Cohort Shotgun Metagenomic Investigation of Colorectal Cancer: Microbial Diversity, Biomarker Discovery, Functional Metagenomics and Independent Validation

TECHNICAL FOCUSR · microbial ecology · taxonomic profiling · functional metagenomics · diversity analysis · differential abundance · cohort-aware statistical modelling

Preview of Decoding Cancer Drug Response Through Integrated Multi-Omics Analysis, Explainable AI and Machine Learning

Open project ↗

PROJECT 05 · Machine learning · multi-omics

Decoding Cancer Drug Response Through Integrated Multi-Omics Analysis, Explainable AI and Machine Learning

TECHNICAL FOCUSPython · machine learning · XGBoost · Random Forest · Elastic Net · SHAP · predictive modelling · model validation · cancer pharmacogenomics